The difference machine (a mechanical machine predating ‘computing’ but doing the same thing, invented in 1820 by Charles Babbage, amazing invention)
Along the same lines Enigma (code cracking machine).
Hope noone will object to these, thay are on a completely different line to my other 2. 
Have we had; the alphabet/writing, money, cooking, condoms, democracy, cooperation, shoes, bow and arrow, steam engine, sailing, central heating, toilets/sewage systems, spectacles (glasses) yet?
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Cement + X-ray machine
Great name for a band.
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Compass
Anesthesia if that hasn’t been said
Gunpowder.
Probably too broad but, the scientific method.
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Cheese
alcohol
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Surely you mean Wine with cheese?
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Birth control measures (condom, contraceptive pill). Imagine the current state of the world if those were not invented.
GPON. If not for this we’d still be stuck with DSL and not seen advanced technologies like robotic surgery etc.
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Still think they aren’t being used enough. Too many fuckwits around the world even now.
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For clarity @cynicaloldgit
I rescind my “joke” candidates of Lucozade Zero and cockrings…
I present…
Cities
Man made, man designed to the betterment and growth of society. The mass movements of people to dedicated spaces, for industry, economy, politics and infrastructure has been the cornerstone of contemporary living. All of this whilst rural living continues to act as an alternative.
Law
Is a manmade construct based upon morals and teachings that can be disputed. Law changes over time, develops as society develops and is a fluid and flexible concept in different cultures.
The central premise is based upon “rules” that guide morals and ethics for centuries.
The most compelling feature of how societies behave today.
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I would imagine that the proportion of little Boris Johnson’s running around would a little lower.
Yeah but still, better have something rather than nothing.
Nominations are now closed.
We didn’t reach 64, so I am going to take out some of the dross and prepare the final thirty two.
And please don’t take it personally if I don’t include one, or both, of your nominations; remember, I hate you all equally.
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Should be wheely fun 
Some classic match ups there.
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Freedom of speech against animal husbandry. That’s a fucking PHD thesis.
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Not to critisize @cynicaloldgit’s decisions, but is freedom of speach an invention or human comcept?