The Corona Pandemic

It’s OK though as pubs are now shutting at 10pm. Everything will be fine :slight_smile:

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Obviously, you can only catch Covid19 in a pub after 10pm. :thinking:

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That’s the way the virus was engineered, clever really.

Engineered that way, you say…

…So, after October the 25th, immunity from Covid, in a pub, will extend to 11pm. :crazy_face:

The amazing thing is the way they got it to understand BST and the seasonal hour change. Those clever Chinese, they think of everything.

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Stop taking the piss,Covid has only just turned 19 and is obviously vulnerable in pubs late at night.

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It’s the lime that kills you in the long run…

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Another reason to despair of humanity.

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I have an aquaintaince that has gone full anti vac.

Sense seems in short supply and as we know from recent political debates you cant tell them they’re wrong (or stupid)

That said i would not put it beyond the UK government to push out a vaccine too early and try to mop up the mess afterwards.

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The NHS app is rated 1.6/5 stars on Google
https://www.covid19.nhs.uk/ (links for iOS and Android)
I’m not reading the reviews as I value my mental health a little, normally I would never use an app so lowly rated.
This app is on my phone until this shit is over.

I think there is a difference between those who refuse on principle, and those who refuse because of concerns that it has been rushed through without full testing.

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This is a massive point I think.

There’s also the question for people that are at a higher risk from Coronavirus. They may really feel that they are gambling.

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Yes. The NYT article @Limiescouse linked to yesterday highlighted three companies including Pfizer and AstraZeneca working on vaccines. Two of the companies were reporting side effects similar to Covid 19 symptoms, and the article pointed out that the rush to get vaccines out to market may mean that these companies may not be required to show it works for those most under threat from severe complications only that it works in cases where people may have light symptoms.

I always ensure my family take vaccines when offered. But this is one occasion when I am wavering about this as my wife and I both have underlying health conditions.

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Same. I want a vaccine to come out but if it’s one that’s pushed out by this UK government I’m certainly going to look into it further.

I am actually far more worried about populations that will take the vaccine, and decide this is all over. I can’t really think of a vaccine that humans need to take every six months, but that still seems the most likely effective term of immunity.

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The only equivalent I can think of is that injection women can get as a contraceptive but even those only typically last for 2-3 months.

I find that forgetting to put the bins out one time is more effective and longer lasting.

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Not “may”. They are not being required to.

There are hundreds of different ways you might use data to answer the question of whether the treatment “works.” If you’re allowed to wait until your data are collected before you decide on your definition it allows you to just play with the data until you get squeeze out the answer you want. To prevent that, drug/biotech companies are required to define ahead of time, in their protocol, what definition they will be using. The regulatory agencies act as partners in this process as they don’t want patients exposed to the risk of an experimental drug in a trial that has too weak a design to allow them to approve the drug at the end of it. Therefore, by the time the first patient is dosed, there is agreement on what the data will have to show for it to be taken as being effective.

There has been a growing movement over the past 20 years to force more up front transparency into what these defined endpoints are, and so I am surprised that Topol is saying we’ve only recently been able to review what the endpoints are for these 3 trials. There is a reasonable discussion to be had over his interpretation of the clinical relevance of these endpoints, but I think it is clear that this definition does not jive with what the average person would think of as the vaccine being shown by studies to “work.”

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Well, it is a good thing that governments aren’t rushing to ink enormous governments that would incentive those corporations to find something to deliver in order to reap the value, even if that did not actually provide much real assistance to extirpation of the virus.

Wait…

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Current Basic Flu vaccines need Renewal every year.

The influenza vaccine doesn’t get renewed every year, it is a different vaccine - aimed at a different variation each year, basically a best guess. Even a year though provides a much more significant window in which immunity applies, albeit in that case only in the years they guessed right.

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