Hopefully not. Do you know what % of cases might be Delta in Germany? In the UK it’s over 90% whereas it currently hardly registers in Denmark (two countries that are doing a lot of sequencing).
Edit: I’ve just found this tweet from a few days ago.
https://mobile.twitter.com/Perbess/status/1406305100642099205
Numbers aren’t 100% reliable due to relatively low numbers of sequencing in some countries but it’s a guide.
I think there supposed to be an update this evening or tommorrow on federal level. Regionally there were very different reports, have heard it might be as high as 25% in Munich. Overall numbers of new infections still going down atm though.
Edit: Apparently 15% in Germany
The reality is we are probably 20 years away from being able to crack the code for true designer protein structure. Probably longer. Its amazingly complex.
For the most part today we struggle to change 1 amino acid of a protein/enzyme, and confidently predict the outcome. When someone wants to engineer a protein they will typically try thousands of combinations using educated guesses. I worked with David Baker (scientist in article) 3 or 4 years ago. He is famous for using scaffold of one enzyme, and changing a key amino acids, to make it perform a new reaction type (really cool but more showing it could be done, than practical enzyme).
Its like Fusion power. When it can be done it will absolutely change the world. Imagine a world were we convert waste gas (eg CO2) into food, plastics, textiles, chemicals. Produced in big fermenters like the ones that make beer. Its already starting to occur today, with basic chemicals (typically natural products eg ethanol by Lanzatech). But with designer enzymes you could make almost anything.
For now, (next 10 to 20 years) the success will come with the automation of biotechnology. Using AI to make making millions of variations in a semi-targeted/educated guess manner, and screening those millions of combinations.
I think this is seriously the problem on both sides of the same coin.
Like in Singapore and a number of countries, we had been criticized for being overly cautious, shutting down when a relatively small number of infections or clusters appear and causing hardships to businesses etc and causing psychological stresses to people.
But in some countries, we see an overly eagerness to open up. A few thousand infections might be lower than tens of thousands but its seem a huge number but it seems that taking it one step at a time seem to be a dirty term in some countries.
I am just wondering is there a right balance and to be fair, governments around the world are equally clueless and everything is fluid at this moment. But I guess the end game for Covid really is to accept that it is endemic and that eventually it will be like a common flu, but the key is managing the stress to your various societal systems until the virus can be managed as such, open up too late, some industries might never recover, open up too early, and your systems might just collapse…
I still think the biggest problem is letting people travel so much.
We go through all the trouble of a successful vaccination program just to let unvaccinated people from other regions mingle with us.
From the start I was gobsmacked at how particularly certain european nations reacted to this pandemic. Travel and tourism has just become economically too important despite it’s ‘nefast’ effects (like spreading nasty stuff, pollution (though not as bad as transporting goods but that isn’t an excuse), obnoxious people spoiling my daughters tranquility …
Fixed it for you.
@Cybernetic_Skrtel really knows their stuff. Could probably teach @ISMF a thing or two.
That too…I cannot understand how people in Europe is not so appreciative of domestic tourism, there is so much beauty within your own country for enough travel…I don’t understand why there is a need to fly to another country for that. To me its just stubborn reckless rebellion, doing it to prove a point…imagine for us in Singapore, no such thing called domestic tourism, where minutes after a plane take off, it leaves the Singapore airspace, where you can drive around the island with not much natural beauty in just one hour. So if anyone needs a holiday overseas…its us haha
Rumour has it he exceptionally good looking and incredibly modest too.
Plus he never forgets passwords.
Very similar to me, but less of a dick 
Cost and reliability of the weather. I grew up in a seaside village in a part of the country where tourism has historically been a big part of the economy, but the reality is you can go to Spain for a fraction of the cost as what it would cost you to spend a week in my part of the world and you don’t have to account for the possibility of it being summer but pissing down with rain the entire time or being 10 degrees.
Where I live in France I can walk 5 minutes and be in lovely settings, river, hill, town center with cinema, historic buildings, museums, ice cream … and plenty of sun most of the summer. If I wish it to be cooler I can go up mountains which are under an hours drive away. I just love it when I make the effort.
In England and Scotland I could get to beaches, hills or historic building on my bike the weather wasn’t so good though.
OK fair…I guess I quite enjoy the gloomy weather in the UK actually and enjoyed driving around the UK…but I am only there for holidays so I cannot speak for those who have lived there for long periods of time and want a change…I think that is fair from that perspective…but still you know considering the current situation and the options you have domestically, albeit not fantastic compared to the others you have around you, the good thing is to stay at home…and I am surprised that for the government to open up so much travel…but again thats me speaking from the other end of the world…so thats only my perspective.
Yeah I wished Singapore has such options but…maybe thats what making staying at home easy…because we have no choice haha!
It seems like Germany is about 5 or 6 weeks behind the UK in vaccinations. Delta will hit in the next week or two if it hasn’t already.
It doesn’t look good.
Well the effect of the Euros would only be known about 8-10 days from now , Either way , it’s madness to allow 80k people inside the stadiums.
they need to stop flying these variants around the world until the vax rate gets up there, and even then I don’t think that vaccinations prevent transmissions. only contracting the virus?
Isn’t it the case that they have only really just started harnessing AI when it comes to protein predictions? With the caveat that I am an idiot with no training in this area, it appeared in the article like the researchers didn’t yet have a strong understanding on how the AI was programmed to look for codon patterns. Surely once this is better understood - by virtue of reverse engineering its successful predictions - then we will learn much more about some of these processes (in addition to having tools that can use brute CPU power to systematically do the perms and coms). That could possibly open up a world of amazing advances in an even shorter time frame?
They do. I think there was a lot of misunderstanding over the implications of the initial approvals that seems to have stuck around. It is harder to demonstrate evidence of reduced transmission and so this was not even considered as part of the initial approvals. Instead they were all based on the ability to mitigate against the development of symptoms. That didnt mean they don’t limit transmission, it was just at that point they didnt have the data to say that. We now do and the effect is very strong for the ones that actually work (looking at you China). There is variability among the different brands, even more so now with the effect of the variants, but thankfully the effect is strong.
We are likely to go into a two-week full-on (what’s that suppose to mean) lockdown from Sunday.
Here we go again. We get lockdown. We pretend that we learnt our lessons. The lockdown is lifted. We start our usual monkey business. Infections shoot-up. We pretend everything is fine. Infections, hospitalization, deaths, rocket. We get lockdown.
